A Nosocomial Cluster of Candida inconspicua Infections in Patients with Hematological Malignancies | Zendy

Domenico D’Antonio | Zendy; Beatrice Violante | Zendy; A Mazzoni | Zendy; T. Bonfini | Zendy; M. Assunta Capuani | Zendy; Francesco D’Aloia | Zendy; A Iacone | Zendy; Francesco Schioppa | Zendy; Ferdinando Romano | Zendy

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A Nosocomial Cluster of Candida inconspicua Infections in Patients with Hematological Malignancies

Author(s) -

Domenico D’Antonio,

Beatrice Violante,

A Mazzoni,

T. Bonfini,

M. Assunta Capuani,

Francesco D’Aloia,

A Iacone,

Francesco Schioppa,

Ferdinando Romano

Publication year - 1998

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.36.3.792-795.1998

Subject(s) - fungemia , fluconazole , biology , microbiology and biotechnology , mycosis , immunology , antifungal

Candida inconspicua was recovered from three patients with hematological malignancies. Two patients had intravenous-catheter-associated fungemia, whereas the third had fungal hepatitis. The three cases of infection occurred over a period of 1 month in patients staying in adjacent single rooms. In vitro susceptibility testing of fungal strains showed all isolates to be resistant to fluconazole, with MICs greater than 32 μg/ml. All of the strains had identical DNA restriction profiles and randomly amplified polymorphic DNA fingerprints. These data suggest a nosocomially acquired infection emanating from a common source within the hospital environment.

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