Study of an outbreak of cefoxitin-resistant Klebsiella pneumoniae in a general hospital
Author(s) -
Maria Gazouli,
M E Kaufmann,
Εva Tzelepi,
H. Dimopoulou,
O. Paniara,
L. S. Tzouvelekis
Publication year - 1997
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.35.2.508-510.1997
Subject(s) - cefoxitin , klebsiella pneumoniae , microbiology and biotechnology , ribotyping , outbreak , penicillin , biology , klebsiella , pulsed field gel electrophoresis , virology , antibiotics , genotype , bacteria , escherichia coli , biochemistry , gene , genetics , staphylococcus aureus
During a 3-month period, six Klebsiella pneumoniae isolates resistant to cefoxitin and penicillin-inhibitor combinations were derived from patients in the intensive care unit of a hospital in Athens, Greece. Enterobacterial repetitive intergenic consensus PCR and pulsed-field gel electrophoresis provided evidence of the clonal origin of the isolates. Conventional techniques and ribotyping were inadequate in proving that the isolates were related. Resistance was due to a plasmidic class C beta-lactamase.
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