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A modified Elek test for detection of toxigenic corynebacteria in the diagnostic laboratory
Author(s) -
Kathryn H. Engler,
T. G. Glushkevich,
И К Мазурова,
Robert C. George,
Androulla Efstratiou
Publication year - 1997
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.35.2.495-498.1997
Subject(s) - corynebacterium diphtheriae , diphtheria , corynebacterium , microbiology and biotechnology , test (biology) , biology , virology , bacteria , botany , genetics , vaccination
The detection of toxigenicity among Corynebacterium diphtheriae and Corynebacterium ulcerans strains is the most important test for the microbiological diagnosis of diphtheria. Difficulties with current methods, in particular the Elek test, are well documented. We therefore describe a modified Elek test which provides an accurate result after only 16 h of incubation, in contrast to 48 h for the conventional test.

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