Monoclonal antibodies against hepatitis A virus | Zendy

A. MacGregor | Zendy; M Kornitschuk | Zendy; John G.R. Hurrell | Zendy; Noreen I. Lehmann | Zendy; A G Coulepis | Zendy; SA Locarnini | Zendy; Ian D. Gust | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Monoclonal antibodies against hepatitis A virus

Author(s) -

A. MacGregor,

M Kornitschuk,

John G.R. Hurrell,

Noreen I. Lehmann,

A G Coulepis,

SA Locarnini,

Ian D. Gust

Publication year - 1983

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.18.5.1237-1243.1983

Subject(s) - monoclonal antibody , virology , antibody , biology , radioimmunoassay , antigen , virus , monoclonal , neutralization , immunology , biochemistry

Three monoclonal antibodies (K2-4F2, K3-2F2, and K3-4C8) of the immunoglobulin G2a class were raised against hepatitis A virus. The specificity of these antibodies was confirmed by immune electron microscopy, solid-phase radioimmunoassay, and in vitro neutralization in cell culture. Binding studies suggested that they all recognize closely related antigenic determinants. These monoclonal antibodies should prove to be of great value as diagnostic and research reagents.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research