Open AccessThe single radial immunodiffusion assay highlights small antigenic differences among influenza virus hemagglutinins
Author(s) -
Stuart J. Rodda,
H. A. GALLICHIO,
Alan Hampson
Publication year - 1981
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.14.5.479-482.1981
Subject(s) - radial immunodiffusion , hemagglutinin (influenza) , immunodiffusion , antiserum , antigen , virology , biology , virus , influenza a virus , orthomyxoviridae , microbiology and biotechnology , antibody , immunology
The results of single radial immunodiffusion assays of influenza virus hemagglutinin were found to be greatly altered by small antigenic differences between test and reference strains. When such differences were present, the precise specificity of the antiserum used had a critical effect on the measured hemagglutinin antigen content obtained.
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