Consequences of the Edge Effect in a Commercial Enzyme-Linked Immunosorbent Assay for the Diagnosis of Lyme Neuroborreliosis | Zendy

Tamara van Gorkom | Zendy; Gijs H. J. van Arkel | Zendy; Willem Voet | Zendy; Steven Thijsen | Zendy; Kristin Kremer | Zendy

Open Access

Consequences of the Edge Effect in a Commercial Enzyme-Linked Immunosorbent Assay for the Diagnosis of Lyme Neuroborreliosis

Author(s) -

Tamara van Gorkom,

Gijs H. J. van Arkel,

Willem Voet,

Steven Thijsen,

Kristin Kremer

Publication year - 2021

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.03280-20

Subject(s) - lyme neuroborreliosis , borrelia , neuroborreliosis , antibody , immunology , medicine , borrelia burgdorferi , serology , cerebrospinal fluid , pleocytosis , biology , virology

The diagnosis of Lyme neuroborreliosis (LNB) is based on neurological symptoms, cerebrospinal fluid (CSF) pleocytosis, and intrathecally producedBorrelia -specific antibodies. In most cases, the presence of intrathecally producedBorrelia -specific antibodies is determined by using an enzyme-linked immunosorbent assay (ELISA).

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