Nanopore Sequencing for Mycobacterium tuberculosis: a Critical Review of the Literature, New Developments, and Future Opportunities | Zendy

Anzaan Dippenaar | Zendy; Sander N. Goossens | Zendy; Melanie Grobbelaar | Zendy; Selien Oostvogels | Zendy; Bart Cuypers | Zendy; Kris Laukens | Zendy; Conor J. Meehan | Zendy; Robin M. Warren | Zendy; Annelies Van Rie | Zendy

Open Access

Nanopore Sequencing for Mycobacterium tuberculosis: a Critical Review of the Literature, New Developments, and Future Opportunities

Author(s) -

Anzaan Dippenaar,

Sander N. Goossens,

Melanie Grobbelaar,

Selien Oostvogels,

Bart Cuypers,

Kris Laukens,

Conor J. Meehan,

Robin M. Warren,

Annelies Van Rie

Publication year - 2021

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.00646-21

Subject(s) - mycobacterium tuberculosis , tuberculosis , nanopore sequencing , mycobacterium , biology , computational biology , microbiology and biotechnology , data science , dna sequencing , medicine , genetics , computer science , pathology , dna

The next-generation, short-read sequencing technologies that generate comprehensive, whole-genome data with single nucleotide resolution have already advanced tuberculosis diagnosis, treatment, surveillance, and source investigation. Their high costs, tedious and lengthy processes, and large equipment remain major hurdles for research use in high tuberculosis burden countries and implementation into routine care.

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