Analytical Performance Characteristics of a New Transcription-Mediated Amplification Assay for Treponema pallidum | Zendy

Damon Getman | Zendy; Mike Lin | Zendy; Nesreen Barakat | Zendy; Rhonda Skvoretz | Zendy; Charmie Godornes | Zendy; Paul D. Swenson | Zendy; Ashley Nenninger | Zendy; Matthew R. Golden | Zendy; Sheila A. Lukehart | Zendy

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Analytical Performance Characteristics of a New Transcription-Mediated Amplification Assay for Treponema pallidum

Author(s) -

Damon Getman,

Mike Lin,

Nesreen Barakat,

Rhonda Skvoretz,

Charmie Godornes,

Paul D. Swenson,

Ashley Nenninger,

Matthew R. Golden,

Sheila A. Lukehart

Publication year - 2021

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.00511-21

Subject(s) - treponema , biology , microbiology and biotechnology , transcription (linguistics) , virology , syphilis , human immunodeficiency virus (hiv) , linguistics , philosophy

This study evaluated the performance characteristics of a new research-use-only transcription-mediated amplification (TMA) assay for the detection of rRNA fromTreponema pallidum . Analytical sensitivity determined using dark-field microscopy-quantitatedT. pallidum was 1.4 organisms/ml (95% confidence interval [CI], 0.7 to 6.33 organisms/ml).

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