Reflex Detection of Ciprofloxacin Resistance in Neisseria gonorrhoeae by Use of the SpeeDx ResistancePlus GC Assay | Zendy

Darren Y. J. Lee | Zendy; Melinda M. Ashcroft | Zendy; Eric P. F. Chow | Zendy; Michelle Sait | Zendy; Vesna De Petra | Zendy; Marlene Tschaepe | Zendy; Sigrid Lange | Zendy; George Taiaroa | Zendy; Catriona S. Bradshaw | Zendy; David M. Whiley | Zendy; Christopher K. Fairley | Zendy; Benjamin P. Howden | Zendy; Marcus Y. Chen | Zendy; Shivani Pasricha | Zendy; Deborah A. Williamson | Zendy

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Reflex Detection of Ciprofloxacin Resistance in Neisseria gonorrhoeae by Use of the SpeeDx ResistancePlus GC Assay

Author(s) -

Darren Y. J. Lee,

Melinda M. Ashcroft,

Eric P. F. Chow,

Michelle Sait,

Vesna De Petra,

Marlene Tschaepe,

Sigrid Lange,

George Taiaroa,

Catriona S. Bradshaw,

David M. Whiley,

Christopher K. Fairley,

Benjamin P. Howden,

Marcus Y. Chen,

Shivani Pasricha,

Deborah A. Williamson

Publication year - 2021

Publication title -

journal of clinical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.349

H-Index - 255

eISSN - 1070-633X

pISSN - 0095-1137

DOI - 10.1128/jcm.00089-21

Subject(s) - neisseria gonorrhoeae , gonorrhea , ciprofloxacin , microbiology and biotechnology , neisseria , neisseriaceae , antibiotic resistance , biology , antibiotics , medicine , virology , bacteria , genetics , human immunodeficiency virus (hiv)

Resistance-guided therapy (RGT) for gonorrhoea may reduce unnecessary use of broad-spectrum antibiotics. When reflexed from the Aptima Combo 2 assay, the ResistancePlus GC assay demonstrated 94.8% sensitivity and 100.0% specificity for Neisseria gonorrhoeae detection.

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