Open AccessReflex Detection of Ciprofloxacin Resistance in Neisseria gonorrhoeae by Use of the SpeeDx ResistancePlus GC Assay
Author(s) -
Darren Y. J. Lee,
M Ashcroft,
Eric P F Chow,
Michelle Sait,
Vesna De Petra,
Marlene Tschaepe,
Sigrid Lange,
George Taiaroa,
Catriona S Bradshaw,
David M. Whiley,
Christopher K Fairley,
Benjamin P. Howden,
Marcus Y Chen,
Shivani Pasricha,
Deborah A Williamson
Publication year - 2021
Publication title -
journal of clinical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.349
H-Index - 255
eISSN - 1070-633X
pISSN - 0095-1137
DOI - 10.1128/jcm.00089-21
Subject(s) - neisseria gonorrhoeae , gonorrhea , ciprofloxacin , microbiology and biotechnology , neisseria , neisseriaceae , antibiotic resistance , biology , antibiotics , medicine , virology , bacteria , genetics , human immunodeficiency virus (hiv)
Resistance-guided therapy (RGT) for gonorrhoea may reduce unnecessary use of broad-spectrum antibiotics. When reflexed from the Aptima Combo 2 assay, the ResistancePlus GC assay demonstrated 94.8% sensitivity and 100.0% specificity for Neisseria gonorrhoeae detection.