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GROWTH INHIBITORY PROPERTIES OF MYCOPLASMA ANTIBODY
Author(s) -
Jack S. Bailey,
Harold W. Clark,
William R. Felts,
Thomas McP. Brown
Publication year - 1963
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.86.1.147-150.1963
Subject(s) - antiserum , biology , mycoplasma , antibody , microbiology and biotechnology , inhibitory postsynaptic potential , antigen , immunology , endocrinology
Bailey, Jack S. (The George Washington University, Washington, D.C.),Harold W. Clark, William R. Felts, and Thomas McP. Brown . Growth inhibitory properties ofMycoplasma antibody. J. Bacteriol.86: 147–150. 1963.—A substance in antiserum responsible for growth inhibition ofMycoplasma was found to be associated with the water-insoluble globulin fraction. This fraction and the agglutinins removed from agglutinated antigen inhibited the growth ofMycoplasma in a similar manner. Sonic oscillation of antiserum broth cultures partially relieved the growth inhibition. The results of this study suggest the existence of neutralizedMycoplasma in a latent phase, which could explain their infrequent detection in tissues and fluids. The application of such techniques as sonic oscillation may improve the recovery and identification ofMycoplasma from these sources.

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