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AMINO ACID CROSS RESISTANCE IN AGROBACTERIUM TUMEFACIENS
Author(s) -
Robert E. Beardsley
Publication year - 1962
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.84.6.1237-1240.1962
Subject(s) - biology , valine , agrobacterium tumefaciens , norleucine , methionine , amino acid , agrobacterium , strain (injury) , glycine , transformation (genetics) , bacteria , biochemistry , microbiology and biotechnology , genetics , gene , anatomy
Beardsley, Robert E. (Manhattan College, New York, N. Y.). Amino acid cross resistance inAgrobacterium tumefaciens . J. Bacteriol.84: 1237–1240. 1962.—Resistant clones selected on medium supplemented with glycine were also resistant tod -methionine,d -valine,dl -norleucine, anddl -serine. Cross resistance was similarly exhibited by clones selected ond -methionine,d -valine, ordl -norleucine. Two types of resistant organisms were observed. One produced colonies containing normal rods on selection medium. The other produced translucent colonies containing L forms. Both grew as typical rods in unsupplemented medium. Some resistant clones did not produce a temperate phage carried by the parental strain, but these retained immunity to homologous phage. The toxicity ofd -methionine andd -valine for nonresistant bacteria is not reversed by thel isomers. The lethal effects of toxic amino acids are additive.

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