ANTIGENIC STUDIES OF CANDIDA

Hasenclever , H. F. (U. S. Public Health Service, Bethesda, Md.),William O. Mitchell, and Joseph Loewe . Antigenic studies of Candida. II. Antigenic relation ofCandida albicans group A and group B toCandida stellatoidea andCandida tropicalis . J. Bacteriol.82: 574–577. 1961.—Previous work in our laboratory has shown the presence of two antigenic groups within the speciesCandida albicans . These groups have been designated as groups A and B. Subsequent studies have been conducted to show the antigenic relationship of these groups withCandida stellatoidea andCandida tropicalis .Antisera to two strains each ofC. albicans group A,C. albicans group B,C. stellatoidea , andC. tropicalis were used in this investigation. Individual suspensions from each of nine strains ofC. stellatoidea and from ten strains each of the other groups and species were used to test the agglutinative properties of unadsorbed and adsorbed antisera. Separate samples of antisera to each immunizing strain were reciprocally cross adsorbed with the other immunizing strains and tested for agglutination.The results indicated thatC. albicans group A andC. tropicalis were antigenically identical andC. albicans group B andC. stellatoidea were antigenically indistinguishable.