Open AccessRole of the yiaR and yiaS Genes of Escherichia coli in Metabolism of Endogenously Formed l -Xylulose
Author(s) -
Ester Ibáñez,
Rosa Gíménez,
Tomas Pedraza,
Laura Baldomà,
Juan Aguilar,
Josefa Badı́a
Publication year - 2000
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.182.16.4625-4627.2000
Subject(s) - escherichia coli , biology , metabolism , biochemistry , mutant , ribulose , gene cluster , gene , escherichia , phosphate , rubisco
GenesyiaP andyiaR of theyiaKLMNOPQRS cluster ofEscherichia coli are required for the metabolism of the endogenously formedl -xylulose, whereasyiaS is required for this metabolism only inaraD mutants. Like AraD, YiaS was shown to havel -ribulose-5-phosphate 4-epimerase activity. Similarity of YiaR to several 3-epimerases suggested that this protein could catalyze the conversion ofl -xylulose-5-phosphate intol -ribulose-5-phosphate, thus completing the pathway betweenl -xylulose and the general metabolism.