Open AccessA developmental stage-specific histone H1 homolog of Coxiella burnetii
Author(s) -
Robert A. Heinzen,
Ted Hackstadt
Publication year - 1996
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.178.16.5049-5052.1996
Subject(s) - biology , histone , coxiella burnetii , nucleoid , histone h1 , schizogony , genetics , dna , microbiology and biotechnology , gene , escherichia coli , immunology , malaria , plasmodium falciparum
Two DNA-binding proteins have been detected in Coxiella burnetii by southwestern (DNA-protein) blotting. One of these, termed Hq1, is enriched in the small cell variant stage of the developmental cycle and displays compositional and primary amino acid sequence similarities to eukaryotic histone H1. C. burnetii appears to be another example of an intracellular parasite with morphologically distinct developmental forms whose nucleoid structure may be controlled by histone H1 homologs.