Open AccessMapping of genes involved in macromolecular synthesis on the chromosome of Streptomyces coelicolor A3(2)
Author(s) -
Gilles P. van Wezel,
Mark J. Buttner,
Erik Vijgenboom,
L. Bosch,
David A. Hopwood,
Helen M. Kieser
Publication year - 1995
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.177.2.473-476.1995
Subject(s) - streptomyces coelicolor , biology , operon , genetics , ribosomal rna , gene , transfer rna , rna polymerase , streptomyces , chromosome , rna , escherichia coli , bacteria , mutant
The genes for the beta, beta', and seven sigma factor subunits of RNA polymerase, for elongation factors EF-Tu1 and EF-Tu3, and for six rRNA operons were mapped on the combined genetic and physical map of the Streptomyces coelicolor chromosome. Like the previously mapped tRNA genes, the RNA polymerase and rRNA genes map to scattered positions. The lack of rRNA operons in the immediate vicinity of the origin of replication (oriC) and the absence of tRNA genes in any of the rRNA operons are novel features of the Streptomyces chromosome.