Open AccessThe TyrR protein of Escherichia coli is a class I transcription activator
Author(s) -
Blair Lawley,
Nobuyuki Fujita,
Akira Ishihama,
A. J. Pittard
Publication year - 1995
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.177.1.238-241.1995
Subject(s) - biology , rna polymerase , transcription (linguistics) , activator (genetics) , escherichia coli , polymerase , rna polymerase ii , microbiology and biotechnology , mutant , enzyme , biochemistry , gene , promoter , gene expression , linguistics , philosophy
The purified TyrR protein and phenylalanine were sufficient to activate in vitro transcription from the tyrP promoter by wild-type RNA polymerase. Such TyrR-mediated activation did not occur when the mutant alpha 235 RNA polymerase was used, indicating that TyrR is a class I transcription activator.