Open AccessPenicillin-Binding Protein 2 Is Essential for the Integrity of Growing Cells ofEscherichia coli ponBStrains
Author(s) -
Francisco Portillo,
Miguel A. de Pedro
Publication year - 1991
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.173.14.4530-4532.1991
Subject(s) - biology , escherichia coli , penicillin binding proteins , microbiology and biotechnology , escherichia coli proteins , penicillin , bacterial protein , penicillin resistance , bacteria , biochemistry , antibiotics , genetics , gene
Analysis of Escherichia coli pbpA(Ts) or rodA(Ts) strains defective for penicillin-binding protein (PBP) 1A or PBP 1B indicated that the activity of PBP 2 is essential to prevent cell lysis in PBP 1B(-) strains and suggested that PBP 2 is active or activatable in rodA(Ts) mutants under restrictive conditions.