Open AccessNonrandom minichromosome replication in Escherichia coli K-12
Author(s) -
L. J. H. Koppes,
Kaspar von Meyenburg
Publication year - 1987
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.169.1.430-433.1987
Subject(s) - minichromosome , biology , minichromosome maintenance , genetics , chromosome , plasmid , replication (statistics) , origin of replication , dna replication , escherichia coli , bacteriophage , dna , gene , virology
The intervals between rounds of chromosome and minichromosome replication were measured by density shift experiments and found to be similar. Thus the minichromosome, a lambda asnA oriC bacteriophage, mostly replicates once each division cycle rather than randomly, despite its high copy number. Slight differences between the chromosome and the oriC plasmid are explained.