Open AccessIdentification of the pleiotropic sacQ gene of Bacillus subtilis
Author(s) -
Maria Yang,
Eugenio Ferrari,
E Chen,
Dennis J. Henner
Publication year - 1986
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.166.1.113-119.1986
Subject(s) - biology , bacillus subtilis , gene , phenotype , plasmid , proteases , genetics , gene expression , gene dosage , allele , pair rule gene , microbiology and biotechnology , regulator gene , biochemistry , bacteria , enzyme
The sacQ gene of Bacillus subtilis, a pleiotropic gene affecting the expression of a number of secreted gene products, has been identified as a small 46-amino-acid polypeptide. The increased expression of this polypeptide in strains carrying the sacQ36 allele, or in strains carrying the sacQ gene on a high copy plasmid, appears to be responsible for the phenotype of higher levels of proteases seen in these strains. A deletion of the sacQ gene had no apparent phenotype, indicating that it is not an essential gene.