Open Accessphs Locus of Escherichia coli, a mutation causing pleiotropic lesions in metabolism, is an rpoA allele
Author(s) -
GEOFFREY C. ROWLAND,
Philip M. Giffard,
Ian R. Booth
Publication year - 1985
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.164.2.972-975.1985
Subject(s) - biology , operon , genetics , allele , locus (genetics) , gene , escherichia coli , rna polymerase , transcription (linguistics) , mutation , l arabinose operon , microbiology and biotechnology , linguistics , philosophy
The phs mutation, which causes a pleiotropic growth defect, has been mapped and shown to be an allele of rpoA, the gene for the alpha subunit of RNA polymerase. The mutation is shown to cause a transcription defect in the arabinose operon, araBAD.
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