Open AccessHybridization studies reveal homologies between pBF4 and pBFTM10, Two clindamycin-erythromycin resistance transfer plasmids of Bacteroides fragilis
Author(s) -
MaryJane Shimell,
C. Jeffrey Smith,
Francis P. Tally,
Francis L. Macrina,
Michael H. Malamy
Publication year - 1982
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.152.2.950-953.1982
Subject(s) - bacteroides fragilis , biology , erythromycin , clindamycin , plasmid , homology (biology) , microbiology and biotechnology , bacteroides , bacteroidaceae , genetics , dna , bacteria , antibiotics , gene
Two clindamycin-erythromycin resistance transfer factors of Bacteroides fragilis, pBF4 and pBFTM10, were analyzed for regions of DNA homology. Although the plasmids were derived from different clinical isolates of B. fragilis and have different sizes, they showed homology in the clindamycin-erythromycin resistance region; no homology could be detected outside of this region.