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Endo-1,4-beta-glucanase formation of Penicillium janthinellum was repressed by glucose, sophorose, and glycerol. Chromatography on DEAE-Sephadex A-50 was employed to separate the 1,4-beta-glucanases from two cellobiases. The 1,4-beta-glucanases were inhibited competitively by cellobiose and glucose, and the two cellobiases were inhibited by glucose and glucono-delta-lactone.

Repression of endo-1,4-beta-glucanase formation in Penicillium janthinellum and product inhibition of its 1,4-beta-glucanases and cellobiases