Deoxyribonucleic acid methylation in mycobacteria | Zendy

Rakesh Kumar Srivastava | Zendy; K. P. Gopinathan | Zendy; T. V. Ramakrishnan | Zendy

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Deoxyribonucleic acid methylation in mycobacteria

Author(s) -

Rakesh Kumar Srivastava,

K. P. Gopinathan,

T. V. Ramakrishnan

Publication year - 1981

Publication title -

journal of bacteriology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.652

H-Index - 246

eISSN - 1067-8832

pISSN - 0021-9193

DOI - 10.1128/jb.148.2.716-719.1981

Subject(s) - biology , mycobacterium smegmatis , microbiology and biotechnology , virulence , dna , mycobacterium , mycobacterium tuberculosis , strain (injury) , methylation , bacteria , tuberculosis , gene , biochemistry , genetics , medicine , pathology , anatomy

Deoxyribonucleic acid modification in six strains of mycobacteria was investigated. The presence of 5-methylcytosine in the virulent strain Mycobacterium tuberculosis H37Rv and its absence in the avirulent strain M. tuberculosis H37Ra and other saprophytic, fast-growing mycobacteria appear to be the salient features. However, deoxyribonucleic acid from M. smegmatis SN2 lysogenized with the temperature phage I3 showed the presence of 5-methylcytosine. All of the strains had N6-methyladenine.

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