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The presence of certainrpsL (strA ) mutations in a strain ofEscherichia coli that cannot synthesize putrescine or spermidine because of deletions in ornithine decarboxylase, arginine decarboxylase, and agmatine ureohydrolase, converts a partial requirement for polyamines for growth into an absolute requirement.

journal of bacteriology

Streptomycin Resistance ( rpsL ) Produces an Absolute Requirement for Polyamines for Growth of an Escherichia coli Strain Unable to Synthesize Putrescine and Spermidine [Δ( speA-speB ) Δ specC ]