Open AccessOrotic acid excretion in some wild-type strains of Escherichia coli K-12
Author(s) -
John Edwin Womack,
Gerard A. O’Donovan
Publication year - 1978
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.136.2.825-827.1978
Subject(s) - uracil , orotic acid , escherichia coli , biology , biochemistry , excretion , dna , mutation , escherichia , enterobacteriaceae , gene , microbiology and biotechnology
During rapid growth, the excretion of pyrimidines, predominantly uracil, is a common phenomenon in procaryotes and eucaryotes. In Escherichia coli, some K-12 strains excrete orotic acid and not uracil. This is caused by a mutation in the pyrF gene.
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