English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

AnEscherichia coli strain carrying therecB21 andres-1 mutations showed an abnormally low level of colony-forming ability although it grew essentially normally in liquid medium. TherecB21 res-1 strain showed little, if any, of the ultraviolet (UV)-induced deoxyribonucleic acid (DNA) breakdown characteristic of theres-1 mutant. Nevertheless, the double mutant was far more sensitive to UV than either theres-1 or therecB21 strain. When compared with a wild-type strain, the rate of release of dimers from UV-irradiated DNA was very slow in therecB21 res-1 , but normal in theres-1 recB + orrecB21 res + mutants. However, the ratio of dimer-to-thymine released into the acid-soluble fraction was three times higher than the wild type inrecB21 res + andrecB21 res-1 and only one-tenth as high as the wild type inres-1 rec + . Alkaline sucrose gradient centrifugation revealed occurrence of single-strand incision of UV-irradiated DNA and the restitution of nicked DNA at a similar rate in therecB21 res-1 andrecB21 res + strains. MutantsuvrC − showed increased amounts of nicks in their DNA with increasing incubation time after UV irradiation, although no detectable amounts of dimers were excised from UV-irradiated DNA. From these results, it is concluded that the increased sensitivity of theres-1 strain to UV light is due to a reduced ability to excise dimers from UV-irradiated DNA and that the high rate of UV-induced breakdown of DNA is not the primary cause. A possible role ofuvrC gene in the excision repair is discussed.

Excision Repair Characteristics of recB − res − and uvrC − Strains of Escherichia coli

Excision Repair Characteristics of recB ⁻ res ⁻ and uvrC ⁻ Strains of Escherichia coli