New Suppressor in Escherichia coli | Zendy

R.R.B. Russell | Zendy; A J Pittard | Zendy

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New Suppressor in Escherichia coli

Author(s) -

R.R.B. Russell,

A J Pittard

Publication year - 1971

Publication title -

journal of bacteriology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.652

H-Index - 246

eISSN - 1067-8832

pISSN - 0021-9193

DOI - 10.1128/jb.107.3.736-740.1971

Subject(s) - biology , escherichia coli , suppressor , strain (injury) , allele , genetics , bacteriophage , mutation , auxotrophy , gene , suppressor mutation , enterobacteriaceae , microbiology and biotechnology , anatomy

During the genetic mapping of a mutation in thepheS gene which confers temperature sensitivity on a strain ofEscherichia coli K-12, an extragenic suppressor was discovered which restores ability to grow at the restrictive temperature. The suppressor, which has been namedsupQ , is cotransduced by bacteriophage P1 with thepurE marker.SupQ does not suppress a number of amber or ochre mutations.SupQ − is carried by the prototrophic Hfr Hayes strain AB259, and the presence of thesupQ − allele impairs the growth of this strain at 42 C.

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