Open AccessListeria monocytogenes Requires the RsbX Protein To Prevent SigB Activation under Nonstressed Conditions
Author(s) -
Ana H. Oliveira,
Teresa Tiensuu,
Duarte Guerreiro,
Hasan Tükenmez,
Charlotte Dessaux,
Francisco Garcı́a-del Portillo,
Conor O’Byrne,
Jörgen Johansson
Publication year - 2022
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.00486-21
Subject(s) - biology , regulon , sigma factor , signal transduction , phosphatase , listeria monocytogenes , phosphorylation , microbiology and biotechnology , biofilm , transcription factor , rna , biochemistry , genetics , bacteria , rna polymerase , gene
Pathogenic bacteria need to sense and respond to stresses to survive harsh environments and also be able to turn off the response when no longer facing stress. Activity of the stress sigma factor SigB in the human pathogenListeria monocytogenes is controlled by a hierarchic system having a large stress-sensing multiprotein complex known as the stressosome at the top.