Calprotectin-Mediated Zinc Chelation Inhibits Pseudomonas aeruginosa Protease Activity in Cystic Fibrosis Sputum | Zendy

Danielle M. Vermilyea | Zendy; Alex W. Crocker | Zendy; Alex H. Gifford | Zendy; Deborah A. Hogan | Zendy

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Calprotectin-Mediated Zinc Chelation Inhibits Pseudomonas aeruginosa Protease Activity in Cystic Fibrosis Sputum

Author(s) -

Danielle M. Vermilyea,

Alex W. Crocker,

Alex H. Gifford,

Deborah A. Hogan

Publication year - 2021

Publication title -

journal of bacteriology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.652

H-Index - 246

eISSN - 1067-8832

pISSN - 0021-9193

DOI - 10.1128/jb.00100-21

Subject(s) - cystic fibrosis , biology , sputum , pseudomonas aeruginosa , calprotectin , microbiology and biotechnology , protease , chelation , zinc , medicine , biochemistry , bacteria , tuberculosis , enzyme , pathology , chemistry , genetics , disease , organic chemistry , inflammatory bowel disease

The factors that contribute to worse outcomes in individuals with cystic fibrosis (CF) with chronicPseudomonas aeruginosa infections are not well understood. Therefore, there is a need to understand environmental factors within the CF airway that contribute toP. aeruginosa colonization and infection.

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