Open AccessPseudomonas aeruginosa Alginate Benefits Staphylococcus aureus?
Author(s) -
Michael J. Schurr
Publication year - 2020
Publication title -
journal of bacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.652
H-Index - 246
eISSN - 1067-8832
pISSN - 0021-9193
DOI - 10.1128/jb.00040-20
Subject(s) - pseudomonas aeruginosa , staphylococcus aureus , biology , microbiology and biotechnology , bacteriology , virulence , pseudomonas , bacteria , pseudomonadaceae , pseudomonadales , staphylococcus , gene , biochemistry , genetics
In this issue of Journal of Bacteriology , Price et al. show that the Pseudomonas aeruginosa -produced exopolysaccharide alginate protects Staphylococcus aureus by dampening the expression of P. aeruginosa virulence products that usually inhibit S. aureus respiration and cell membrane integrity when the two organisms compete in other environments (C. E. Price, D. G. Brown, D. H. Limoli, V. V. Phelan, and G. A. O'Toole, J Bacteriol 202:e00559-19, 2020, https://doi.org/10.1128/jb.00559-19). This is the first report that exogenously added alginate affects P. aeruginosa competition and provides a partial explanation for S. aureus and P. aeruginosa coinfections in cystic fibrosis.