Open AccessExtracellular antigens of serotype III group B streptococci
Author(s) -
Terence I. Doran,
David C. Straus,
S J Mattingly
Publication year - 1980
Publication title -
infection and immunity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.508
H-Index - 220
eISSN - 1070-6313
pISSN - 0019-9567
DOI - 10.1128/iai.30.3.890-893.1980
Subject(s) - antigen , biology , serotype , microbiology and biotechnology , extracellular , streptococcus , streptococcaceae , group a , sialic acid , chemically defined medium , size exclusion chromatography , bacteria , biochemistry , in vitro , immunology , enzyme , medicine , genetics , antibiotics
Two sialic acid-containing type III group B streptococcal antigens were obtained from a supernatant growth medium, purified by anion exchange or gel filtration, and found to be free of group B reactivity. Quantitation of the high-molecular-weight extracellular type III antigen indicated that approximately 20-fold more antigen was recoverable from the growth medium than could be obtained by neutral buffer extraction of whole cells.