Open AccessHeterotypic immunity to influenza in ferrets
Author(s) -
Robert A. Yetter,
William H. Barber,
Parker A. Small
Publication year - 1980
Publication title -
infection and immunity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.508
H-Index - 220
eISSN - 1070-6313
pISSN - 0019-9567
DOI - 10.1128/iai.29.2.650-653.1980
Subject(s) - biology , immunity , virology , heterologous , virus , viral shedding , orthomyxoviridae , influenza a virus , immunology , immune system , biochemistry , gene
Heterotypic immunity to influenza virus in ferrets operated against heterotypic influenza viruses but not heterologous viruses. Contrary to prior reports, the protection conferred lasted for at least 18 months. This type of immunity limited virus shedding but did not prevent infection. These results suggest that this phenomenon could play a role in determining the severity of infections caused by type A influenza viruses in humans.