Open AccessThe Innate Immune Response in the Marmoset during the Acute Pneumonic Disease Caused by Burkholderia pseudomallei
Author(s) -
Sarah A. Ngugi,
Thomas R. Laws,
Andrew J. H. Simpson,
Michelle Nelson
Publication year - 2022
Publication title -
infection and immunity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.508
H-Index - 220
eISSN - 1070-6313
pISSN - 0019-9567
DOI - 10.1128/iai.00550-21
Subject(s) - burkholderia pseudomallei , melioidosis , innate immune system , biology , immunology , marmoset , immune system , microbiology and biotechnology , bacteria , paleontology , genetics
Burkholderia pseudomallei is the causative agent of melioidosis, a severe human infection that is difficult to treat with antibiotics and for which there is no effective vaccine. Development of novel treatments rely upon appropriately characterized animal models.