Open AccessInclusion Membrane Growth and Composition Are Altered by Overexpression of Specific Inclusion Membrane Proteins in Chlamydia trachomatis L2
Author(s) -
Macy G Olson-Wood,
Lisa M. Jorgenson,
Scot P. Ouellette,
Elizabeth A. Rucks
Publication year - 2021
Publication title -
infection and immunity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.508
H-Index - 220
eISSN - 1070-6313
pISSN - 0019-9567
DOI - 10.1128/iai.00094-21
Subject(s) - chlamydia trachomatis , biology , chlamydiae , inclusion bodies , microbiology and biotechnology , membrane protein , vacuole , chlamydiaceae , cytoplasm , virology , gene , membrane , biochemistry , recombinant dna
Chlamydia trachomatis is the leading cause of bacterial sexually transmitted infections. This obligate intracellular bacterium develops within a membrane-bound vacuole called an inclusion, which sequesters the chlamydiae from the host cytoplasm. Host-pathogen interactions at this interface are mediated by chlamydial inclusion membrane proteins (Incs).