Genome Sequence of the Bile Salt-Degrading Bacterium Novosphingobium sp. Strain Chol11, a Model Organism for Bacterial Steroid Catabolism | Zendy

Onur Yücel | Zendy; Daniel Wibberg | Zendy; Bodo Philipp | Zendy; Jörn Kalinowski | Zendy

Open Access

Genome Sequence of the Bile Salt-Degrading Bacterium Novosphingobium sp. Strain Chol11, a Model Organism for Bacterial Steroid Catabolism

Author(s) -

Onur Yücel,

Daniel Wibberg,

Bodo Philipp,

Jörn Kalinowski

Publication year - 2018

Publication title -

genome announcements

Language(s) - English

Resource type - Journals

ISSN - 2169-8287

DOI - 10.1128/genomea.01372-17

Subject(s) - biology , whole genome sequencing , strain (injury) , bacteria , catabolism , organism , steroid , gene , microbiology and biotechnology , phylogenetic tree , genome , biochemistry , genetics , enzyme , hormone , anatomy

Many bacteria from different phylogenetic groups are able to degrade eukaryotic steroid compounds, but the underlying metabolic pathways are still not well understood. Novosphingobium sp. strain Chol11 is a steroid-degrading alphaproteobacterium. Its genome sequence reveals that it lacks several genes for steroid degradation known to exist in other model organisms.

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