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Whole-Genome Sequencing of Lactobacillus Species from Two Commercial Probiotic Products
Author(s) -
Anna Colavecchio,
Victoria Leo,
Sophia Zaccheo,
Julie Jeukens,
Jean-Guillaume Emond-Rhéault,
Jérémie Hamel,
Iréna Kukavica-Ibrulj,
Roger C. Lévesque,
Lawrence Goodridge
Publication year - 2017
Publication title -
genome announcements
Language(s) - English
Resource type - Journals
ISSN - 2169-8287
DOI - 10.1128/genomea.01279-17
Subject(s) - efflux , probiotic , biology , antibiotics , microbiology and biotechnology , genome , lactobacillus , antibiotic resistance , bacterial genetics , genetics , bacteria , gene , escherichia coli
Eight Lactobacillus strains, each intrinsically resistant to an antibiotic, were isolated from two commercial probiotic products. Whole-genome sequencing identified two efflux transporters, a multidrug and extrusion protein (MATE) efflux transporter, and LmrCD, which may contribute to their intrinsic antibiotic resistance and may therefore facilitate their survival in the intestinal microbiota following antibiotic therapy.

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