Open AccessComplete Genome Sequence of Multidrug-Resistant Clinical Isolate Mycobacterium tuberculosis 187.0, Used To Study the Effect of Drug Susceptibility Reversion by the New Medicinal Drug FS-1
Author(s) -
А. И. Ильин,
Murat E. Kulmanov,
Ilya S. Korotetskiy,
Gulshara K. Akhmetova,
Marina V. Lankina,
Sergey V. Shvidko,
Oleg N. Reva
Publication year - 2015
Publication title -
genome announcements
Language(s) - English
Resource type - Journals
ISSN - 2169-8287
DOI - 10.1128/genomea.01272-15
Subject(s) - reversion , mycobacterium tuberculosis , multiple drug resistance , tuberculosis , biology , drug resistance , whole genome sequencing , drug , genome , population , genetics , microbiology and biotechnology , pharmacology , gene , medicine , phenotype , pathology , environmental health
Complete genome sequence of the multidrug-resistant clinical isolate Mycobacterium tuberculosis SCAID 187.0 containing several drug-resistance mutations is presented. This strain is used in experiments to study genomic and population changes leading to reversion of susceptibility to the 1st line anti-tuberculosis (TB) drugs under the influence of a new medicinal drug FS-1.