First Insight into the Genome Sequences of Two Linezolid-Resistant Nocardia farcinica Strains Isolated from Patients with Cystic Fibrosis | Zendy

Sylvia Valdezate | Zendy; Sara Monzón | Zendy; Noelia Garrido | Zendy; Ángel Zaballos | Zendy; María J. Medina-Pascual | Zendy; José Manuel Azcona | Zendy; Begoña Vilar | Zendy; Isabel Cuesta | Zendy

Open Access

First Insight into the Genome Sequences of Two Linezolid-Resistant Nocardia farcinica Strains Isolated from Patients with Cystic Fibrosis

Author(s) -

Sylvia Valdezate,

Sara Monzón,

Noelia Garrido,

Ángel Zaballos,

María J. Medina-Pascual,

José Manuel Azcona,

Begoña Vilar,

Isabel Cuesta

Publication year - 2017

Publication title -

genome announcements

Language(s) - English

Resource type - Journals

ISSN - 2169-8287

DOI - 10.1128/genomea.01212-17

Subject(s) - linezolid , 23s ribosomal rna , biology , microbiology and biotechnology , genome , cystic fibrosis , trimethoprim , whole genome sequencing , sulfamethoxazole , genetics , gene , bacteria , antibiotics , staphylococcus aureus , ribosome , rna , vancomycin

The draft genome sequences of two Nocardia farcinica strains isolated from two patients with cystic fibrosis (CF), resistant to trimethoprim/sulfamethoxazole and linezolid, are reported here. The estimated genome sizes were 5.8 Mb with a 70.63% G+C content. Transposases from Tn 916 were detected, but not 23S rRNA mutation (G2576T) related to linezolid resistance.

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