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Draft Genome Sequence of Streptomyces sp. TP-A0874, a Catechoserine Producer
Author(s) -
Hisayuki Komaki,
Akira Hosoyama,
Natsuko Ichikawa,
Yasuhiro Igarashi
Publication year - 2016
Publication title -
genome announcements
Language(s) - English
Resource type - Journals
ISSN - 2169-8287
DOI - 10.1128/genomea.01163-16
Subject(s) - biology , nonribosomal peptide , polyketide , whole genome sequencing , gene cluster , genome , streptomyces , strain (injury) , gene , genetics , sequence (biology) , computational biology , biosynthesis , bacteria , anatomy
We report the draft genome sequence of Streptomyces sp. TP-A0874 isolated from compost. This strain produces catechoserine, a new catecholate-type inhibitor of tumor cell invasion. The genome harbors at least six gene clusters for polyketide and nonribosomal peptide biosyntheses. The biosynthetic gene cluster for catechoserines was identified by bioinformatic analysis.

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