Draft Genome Sequence of Marine-Derived Bacillus subtilis TP-B0611, a Producer of Bacilosarcins and Amicoumacins | Zendy

Hisayuki Komaki | Zendy; Akira Hosoyama | Zendy; Natsuko Ichikawa | Zendy; Yasuhiro Igarashi | Zendy

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Draft Genome Sequence of Marine-Derived Bacillus subtilis TP-B0611, a Producer of Bacilosarcins and Amicoumacins

Author(s) -

Hisayuki Komaki,

Akira Hosoyama,

Natsuko Ichikawa,

Yasuhiro Igarashi

Publication year - 2016

Publication title -

genome announcements

Language(s) - English

Resource type - Journals

ISSN - 2169-8287

DOI - 10.1128/genomea.01134-16

Subject(s) - nonribosomal peptide , bacillus subtilis , polyketide synthase , biology , gene cluster , gene , genome , genetics , whole genome sequencing , biosynthesis , polyketide , computational biology , bacteria

Here, we report the draft genome sequence of Bacillus subtilis TP-B0611, which produces the isocoumarin-type compounds bacilosarcin and amicoumacin. The genome encodes three nonribosomal peptide synthetase (NRPS) gene clusters and one hybrid polyketide synthase (PKS)/NRPS gene cluster. The hybrid PKS/NRPS gene cluster was identified to be responsible for the biosynthesis of bacilosarcins and amicoumacins.

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