Open Access
Complete Genome Sequences of Helicobacter pylori Clarithromycin-Resistant Strains
Author(s) -
Tran Thanh Binh,
Rumiko Suzuki,
Seiji Shiota,
Dong H. Kwon,
Yoshio Yamaoka
Publication year - 2013
Publication title -
genome announcements
Language(s) - English
Resource type - Journals
ISSN - 2169-8287
DOI - 10.1128/genomea.00912-13
Subject(s) - clarithromycin , helicobacter pylori , biology , genome , strain (injury) , microbiology and biotechnology , whole genome sequencing , selection (genetic algorithm) , genetics , gene , anatomy , artificial intelligence , computer science
We report the complete genome sequences of two Helicobacter pylori clarithromycin-resistant strains. Clarithromycin (CLR)-resistant strains were obtained under the exposure of H. pylori strain 26695 on agar plates with low clarithromycin concentrations. The genome data provide insights into the genomic changes of H. pylori under selection by clarithromycin in vitro.