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Cattle are the primary reservoir ofEscherichia coli O157:H7, the most frequently isolated serotype of enterohemorrhagicE. coli infections among humans in North America. To evaluate the diversity ofE. coli O157:H7 isolates within a single dairy herd, the genomes of 30 isolates collected over a 7-year period were sequenced.

Genome Sequences of 30 Escherichia coli O157:H7 Isolates Recovered from a Single Dairy Farm and Its Associated Off-Site Heifer-Raising Facility