Open AccessGenome Sequence of Tumor Virus X, a Member of the Genus Protoparvovirus in the Family Parvoviridae
Author(s) -
Ellen M. Vollmers,
Anthony D’Abramo,
Susan F. Cotmore,
Peter Tattersall
Publication year - 2014
Publication title -
genome announcements
Language(s) - English
Resource type - Journals
ISSN - 2169-8287
DOI - 10.1128/genomea.00758-14
Subject(s) - biology , parvoviridae , genus , whole genome sequencing , genome , sequence (biology) , virus , virology , genetics , virus classification , evolutionary biology , parvovirus , zoology , gene
The orphan parvovirus tumor virus X (TVX) has potent oncolytic activity. Compared to other viruses from the species Rodent protoparvovirus 1, TVX has a 111 nucleotide deletion in its nonstructural (NS) gene, a 24 nucleotide insertion in VP1, and a 93 nucleotide repeat initiating from the C-terminus of the capsid gene.