Complete Genome Sequence of the First KPC-Type Carbapenemase-Positive Proteus mirabilis Strain from a Bloodstream Infection | Zendy

Vincenzo Di Pilato | Zendy; Adriana Chiarelli | Zendy; Christine J. Boinett | Zendy; Eleonora Riccobono | Zendy; Simon R. Harris | Zendy; Marco Maria D’Andrea | Zendy; Nicholas R. Thomson | Zendy; Gian María Rossolini | Zendy; Tommaso Giani | Zendy

Open Access

Complete Genome Sequence of the First KPC-Type Carbapenemase-Positive Proteus mirabilis Strain from a Bloodstream Infection

Author(s) -

Vincenzo Di Pilato,

Adriana Chiarelli,

Christine J. Boinett,

Eleonora Riccobono,

Simon R. Harris,

Marco Maria D’Andrea,

Nicholas R. Thomson,

Gian María Rossolini,

Tommaso Giani

Publication year - 2016

Publication title -

genome announcements

Language(s) - English

Resource type - Journals

ISSN - 2169-8287

DOI - 10.1128/genomea.00607-16

Subject(s) - proteus mirabilis , klebsiella pneumoniae , biology , whole genome sequencing , strain (injury) , plasmid , chromosome , microbiology and biotechnology , genome , genetics , gene , escherichia coli , anatomy

Sequencing of the blaKPC-positive strain Proteus mirabilis AOUC-001 was performed using both the MiSeq and PacBio RS II platforms and yielded a single molecule of 4,272,433 bp, representing the complete chromosome. Genome analysis showed the presence of several acquired resistance determinants, including two copies of blaKPC-2 carried on a fragment of a KPC-producing plasmid previously described in Klebsiella pneumoniae.

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