Draft Genome Sequences of Clinical Daptomycin-Nonsusceptible Methicillin-Resistant Staphylococcus aureus Strain APS211 and Its Daptomycin-Susceptible Progenitor APS210 | Zendy

David R. Cameron | Zendy; JhihHang Jiang | Zendy; Iain J. Abbott | Zendy; Denis W. Spelman | Zendy; Anton Y. Peleg | Zendy

Open Access

Draft Genome Sequences of Clinical Daptomycin-Nonsusceptible Methicillin-Resistant Staphylococcus aureus Strain APS211 and Its Daptomycin-Susceptible Progenitor APS210

Author(s) -

David R. Cameron,

JhihHang Jiang,

Iain J. Abbott,

Denis W. Spelman,

Anton Y. Peleg

Publication year - 2015

Publication title -

genome announcements

Language(s) - English

Resource type - Journals

ISSN - 2169-8287

DOI - 10.1128/genomea.00568-15

Subject(s) - daptomycin , staphylococcus aureus , biology , strain (injury) , microbiology and biotechnology , whole genome sequencing , genome , gene , genetics , bacteria , vancomycin , anatomy

To assess the genetic factors contributing to daptomycin resistance in Staphylococcus aureus, the draft genome of a clinically derived daptomycin-nonsusceptible isolate APS211 was generated and compared to the draft sequence of its susceptible progenitor strain APS210. Four genetic differences were identified including a previously described mutation within the mprF gene.

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