Open AccessWhole-Genome Sequencing Analysis of Methicillin-Resistant Staphylococcus simulans Causing Surgical Site Infection
Author(s) -
Jian Chen,
Qiang Fang
Publication year - 2016
Publication title -
genome announcements
Language(s) - English
Resource type - Journals
ISSN - 2169-8287
DOI - 10.1128/genomea.00555-16
Subject(s) - biology , whole genome sequencing , fibronectin , genome , staphylococcus aureus , pathogenesis , elastin , microbiology and biotechnology , genetics , gene , bacteria , immunology , cell
Staphylococcus simulans is a normal part of the microbiota in humans and animals and is rarely associated with human invasive infections. We present here the genome sequence of S. simulans CJ16, which caused the first case of surgical site infection. Adhesion proteins, including fibronectin-binding protein (FnbA), elastin-binding protein (EbpS), and cell wall-anchored protein (SasA, SasF, and SasH), were detected in the genome, which might promote the survival of S. simulans on human skin and pathogenesis of infections.