Single Passage of Human Metapneumovirus in LLC-MK2 Cells Does Not Affect Viral Protein-Coding Capacity | Zendy

Simon Loevenich | Zendy; Aleksandr Ianevski | Zendy; Eneli Oitmaa | Zendy; Denis E. Kainov | Zendy; Marit W. Anthonsen | Zendy

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Single Passage of Human Metapneumovirus in LLC-MK2 Cells Does Not Affect Viral Protein-Coding Capacity

Author(s) -

Simon Loevenich,

Aleksandr Ianevski,

Eneli Oitmaa,

Denis E. Kainov,

Marit W. Anthonsen

Publication year - 2018

Publication title -

genome announcements

Language(s) - English

Resource type - Journals

ISSN - 2169-8287

DOI - 10.1128/genomea.00440-18

Subject(s) - human metapneumovirus , metapneumovirus , biology , genome , virology , affect (linguistics) , coding region , virus , nucleotide , genetics , gene , respiratory system , respiratory tract infections , communication , anatomy , sociology

Here, we report the complete genome sequences of human metapneumovirus (HMPV) prior to and after passaging in LLC-MK2 cells. Paired comparisons of the 13,335-nucleotide genomes revealed that the virus acquired the T10736C transition in its genome, which did not affect the amino acid sequences of HMPV proteins.

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