Draft Genome Sequence of the Tacrolimus-Producing Bacterium Streptomyces tsukubaensis F601 | Zendy

Gongli Zong | Zendy; Chuanqing Zhong | Zendy; Jiafang Fu | Zendy; Ronghuo Qin | Zendy; Guangxiang Cao | Zendy

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Draft Genome Sequence of the Tacrolimus-Producing Bacterium Streptomyces tsukubaensis F601

Author(s) -

Gongli Zong,

Chuanqing Zhong,

Jiafang Fu,

Ronghuo Qin,

Guangxiang Cao

Publication year - 2017

Publication title -

genome announcements

Language(s) - English

Resource type - Journals

ISSN - 2169-8287

DOI - 10.1128/genomea.00385-17

Subject(s) - whole genome sequencing , biology , bacteria , streptomyces , tacrolimus , genome , sequence (biology) , genetics , computational biology , microbiology and biotechnology , gene , medicine , transplantation

Streptomyces tsukubaensis strain F601 was found to be a producer of the immunosuppressive drug tacrolimus. The draft genome sequence of this strain was approximately 8.52 Mbp. Genes involved in the biosynthesis of tacrolimus were identified in the genome. This draft genome sequence will provide insights into the genetic basis of tacrolimus biosynthesis and regulation.

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