Genomic Analysis of Broad-Host-Range Enterobacteriophage Av-05 | Zendy

Luis Amarillas | Zendy; Osvaldo López-Cuevas | Zendy; Josefina LeónFélix | Zendy; Nohelia Castrodel Campo | Zendy; Charles P. Gerba | Zendy; Cristóbal Cháidez | Zendy

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Genomic Analysis of Broad-Host-Range Enterobacteriophage Av-05

Author(s) -

Luis Amarillas,

Osvaldo López-Cuevas,

Josefina LeónFélix,

Nohelia Castrodel Campo,

Charles P. Gerba,

Cristóbal Cháidez

Publication year - 2015

Publication title -

genome announcements

Language(s) - English

Resource type - Journals

ISSN - 2169-8287

DOI - 10.1128/genomea.00282-15

Subject(s) - lytic cycle , orfs , biology , bacteriophage , genome , open reading frame , genetics , salmonella , host (biology) , serotype , escherichia coli , computational biology , bacteria , microbiology and biotechnology , gene , virus , peptide sequence

Lytic bacteriophages have reemerged as an alternative for the control of pathogenic bacteria. However, the effective use of phage relies on appropriate genomic characterization. In this study, we report the genome of bacteriophage Av-05 and its sequence analysis, which has strong lytic activity against Escherichia coli O157:H7 strains and several Salmonella serotypes. The analysis revealed that the phage Av-05 genome consists of 120,938 bp, containing 209 putative open reading frames (ORFs) and 9 tRNAs.

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