Open AccessComplete Sequence of the Intronless Mitochondrial Genome of the Saccharomyces cerevisiae Strain CW252
Author(s) -
Delphine Naquin,
Cristina Panozzo,
Geneviève Dujardin,
Erwin van Dijk,
Yves d’Aubenton-Carafa,
Claude Thermes
Publication year - 2018
Publication title -
genome announcements
Language(s) - English
Resource type - Journals
ISSN - 2169-8287
DOI - 10.1128/genomea.00219-18
Subject(s) - saccharomyces cerevisiae , strain (injury) , biology , sequence (biology) , whole genome sequencing , genetics , mitochondrial dna , genome , computational biology , yeast , gene , anatomy
The mitochondrial genomes of Saccharomyces cerevisiae strains contain up to 13 introns. An intronless recombinant genome introduced into the nuclear background of S. cerevisiae strain W303 gave the S. cerevisiae CW252 strain, which is used to model mitochondrial respiratory pathologies. The complete sequence of this mitochondrial genome was obtained using a hybrid assembling methodology.